Lionel Augeul Selected Research

(melle-4)cyclosporin

7/2013	Endoplasmic reticulum stress contributes to heart protection induced by cyclophilin D inhibition.
1/2011	Inhibition of mitochondrial permeability transition to prevent the post-cardiac arrest syndrome: a pre-clinical study.
1/2008	Increased mitochondrial calcium coexists with decreased reperfusion injury in postconditioned (but not preconditioned) hearts.

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Lionel Augeul Research Topics

Disease

7	Ischemia 01/2019 - 01/2008
5	Reperfusion Injury 01/2017 - 01/2008
3	Infarction (Infarctions) 03/2014 - 01/2008
1	Acute-Phase Reaction 01/2019
1	Inflammation (Inflammations) 01/2019
1	Metabolic Diseases (Metabolic Disease) 01/2017
1	Necrosis 01/2017
1	Myocardial Reperfusion Injury 01/2017
1	Ventricular Remodeling 09/2011
1	Myocardial Infarction 09/2011
1	Wounds and Injuries (Trauma) 01/2011
1	Renal Insufficiency (Renal Failure) 01/2011

Drug/Important Bio-Agent (IBA)

6	Mitochondrial Permeability Transition PoreIBA 01/2019 - 01/2008
4	Cyclosporine (Ciclosporin)FDA LinkGeneric 01/2017 - 06/2009
3	salicylhydroxamic acid (SHAM)IBA 01/2019 - 06/2009
3	(melle-4)cyclosporinIBA 07/2013 - 01/2008
2	Coloring Agents (Dyes)IBA 07/2013 - 01/2008
2	triphenyltetrazoliumIBA 07/2013 - 01/2008
1	Interleukin-6 (Interleukin 6)IBA 01/2019
1	Serine (L-Serine)FDA Link 01/2019
1	Proteins (Proteins, Gene)FDA Link 01/2017
1	CaspasesIBA 01/2017
1	GhrelinIBA 01/2017
1	Tissue Inhibitor of Metalloproteinase-1IBA 03/2014
1	ursodoxicoltaurineIBA 07/2013
1	Cyclophilins (Cyclophilin)IBA 07/2013
1	Alanine Transaminase (SGPT)IBA 01/2011
1	TroponinIBA 01/2011
1	CreatinineIBA 01/2011
1	Lactic Acid (Lactate)FDA LinkGeneric 01/2011
1	1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA 06/2009
1	CalciumIBA 01/2008

Therapy/Procedure

2	Ischemic Postconditioning 04/2015 - 09/2011
1	Injections 01/2017
1	Resuscitation 01/2011